acute myeloid leukemia cell line – acute myeloid leukemia life expectancy
Acute Myeloid Leukemia Cell Line, AML cell lines harboring either a SF mutation or high expression of the DCAF15 protein exhibited particular sensitivity to sulphonamides, which were shown to induce DCAF15-mediated degradation of SF RBM39 Han et al,, 2017;
Human myeloid leukemia cell lines: a review
FLT3 mutations in acute myeloid leukemia cell lines
Acute Myeloid Leukemia Cell Line
· Acute myeloid leukemia AML is characterized by a clonal proliferation of myeloid precursors that fail to differentiate into more mature hematopoietic cells Compared with normal cells leukemic cells have been reported to have lower respiratory chain complex activity and lower spare reserve capacity in the respiratory chain balanced by an increase in mitochondrial biogenesis [1]
Acute myeloid leukemia cell-derived extracellular vesicles
· Several human acute myeloid leukemia cell lines were recently established, These lines provide useful model systems to study the control of differentiation in human myelogenous leukemia and, in a broader framework, the controls of normal myeloid development, The K562 line is composed of undifferentiated blast cells that are rich in glycophorin and may be induced to produce fetal and embryonic hemoglobin in the presence of hemin, The KG-1 cell line …
New acute myeloid leukemia-derived cell line: MUTZ-8 with
Acute Myeloid Leukemia Cell Line, AML cell lines harboring either a SF mutation or high expression of the DCAF15 protein exhibited particular sensitivity to sulphonamides, which were shown to induce DCAF15-mediated degradation of SF RBM39 Han et al,, 2017; From: Drug Resistance Updates, 2020,
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| Human myeloid leukemia cell lines: a review | pubmed,ncbi,nlm,nih,gov |
| Aml Cell Lines , ATCC , Bioz | www,bioz,com |
| Human myeloid leukemia cell lines: a review , Blood | ashpublications,org |
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microRNAs miRNAs or miRs can be delivered from acute myeloid leukemia AML cells to hematopoietic stem cells HSCs to regulate hematopoietic function via extracellular vesicles EVs In this
FLT3 mutations in acute myeloid leukemia cell lines
· The new leukemia cell line MUTZ-8 which displays mainly myeloid characteristics has been derived from a patient with acute myeloid leukemia AML with a history of myelodysplastic syndromes
Mitochondria in human acute myeloid leukemia cell lines
· Quentmeier, H,, Reinhardt, J,, Zaborski, M, et al, FLT3 mutations in acute myeloid leukemia cell lines, Leukemia 17, 120–124 2003, https://doi,org/10,1038/sj,leu,2402740, Download citation
Mitochondria in human acute myeloid leukemia cell lines
acute myeloid leukemia cell line
· Induction of differentiation of the acute myeloid leukemia cell line HL-60 by a securinine dimer Wen Hou 1 Zhen-Ya Wang 1 Jing Lin 1 & Wei-Min Chen ORCID: orcid,org/0000-0002-0292-7841 1
Acute Myeloid Leukemia Cell Line
Several human acute myeloid leukemia cell lines were recently established These lines provide model systems to study the control of differentiation in human myelogenous leukemia and in a broader framework the controls of normal myeloid development, The K562 line is composed of undifferentiated blast cells that are rich in glycophorin and may be induced to produce fetal and embryonic hemoglobin in the presence of hemin, The KG-1 cell line …
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In this study we report the use of complementary peptide antigen enrichment methods and a comprehensive mass spectrometric acquisition strategy to provide in-depth immunopeptidome data for the THP-1 cell line a cell line used widely as a model of human leukaemia To accomplish this we combined robust experimental workflows that incorporated ultrafiltration or off-line reversed phase chromatography to enrich peptide ligand …
Induction of differentiation of the acute myeloid leukemia
FLT3 mutations in acute myeloid leukemia cell lines Internal tandem duplications ITD and D835 point mutations of the receptor tyrosine kinase RTK FLT3 are found in a high proportion of cases with acute myeloid leukemia AML These genetic aberrations may lead to the constitutive activation of the receptor thus providing the molecular basis
In-depth mining of the immunopeptidome of an acute myeloid
As a consequence functional mitochondrial disorders are involved in many human cancers including acute myeloid leukemia AML However very few data are available on the deregulation of their number and/or shape in leukemic cells despite the evident link between ultrastructure and function In this context we analyzed the ultrastructural mitochondrial parameters number per cell, mitochondria area, number of cristae/mitochondria, cristal thickness in five leukemia cell lines …
Establishment of a human acute myeloid leukemia cell line
Human Myeloid Leukemia Cell Lines: A Review
· A novel leukemic cell line with an 8;21 chromosome translocation designated as Kasumi-1 was established from the peripheral blood of a 7-year-old boy suffering from acute myeloid leukemia AML The Kasumi- 1 cells were positive for myeloperoxidase showing a morphology of myeloid maturation The response in proliferation assay was observed in the culture with interleukin-3 IL-3 IL-6 granulocyte colony- …