cited4 gene
CITED4 Gene – genomics-online,com
CITED4
Gene
· positive regulation of transcription, DNA-templated Source: MGI, Inferred from direct assay i, Ref,1, “Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells,”
Complete information for CITED4 gene protein-coding, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4, including: function, proteins, disorders, pathways, orthologs, and expression, GeneCards – The Human Gene Compendium
· “CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha,” Fox S,B, , Braganca J, , Turley H, , Campo L, , Han C, , Gatter K,C, , Bhattacharya S, , Harris A,L, Cancer Res, 64:6075-60812004 [ PubMed ] [ Europe PMC ] [ Abstract ]
CITED4 gene silencing in colorectal cancer cells modulates
Cited4
· CITED4 CREB-binding protein/P300-interacting transactivator with ED-rich tail member 4 is one member of the CITED family of proteins known to participate in the regulatory activity of several genes including TGFB ER TFAP2 and HIF1A CITED1 msg1 CITED2 mrg1, p35srg and CITED4 mrg2 were originally identified as a family of homologous proteins possessing a conserved transactivating CR2 domain that …
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By using microarray-based expression profiling we found that oligodendroglial tumours with 1p and 19q losses showed significantly lower expression of the CBP/p300-interacting transactivator with glutamic acid/aspartic acid-rich carboxyl-terminal domain 4 gene CITED4 at 1p34,2 as compared to tumours without 1p and 19q losses Mutational analysis showed no CITED4 mutations in gliomas However, 1p and 19q losses as well as low expression of CITED4 …
CITED4 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, CITED4 Genome Browser, CITED4 References CITED4 – Explore an overview of CITED4, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data,
Our study results suggest that the Cited4 gene is related to cardiac differentiation and maintenance of proliferation capacity of embryonic stem cell-derived cardiomyocytes during in vitro cardiogenesis Therefore manipulation of Cited4 gene expression may be of great interest for cardiac regeneration
CITED4 gene silencing in colorectal cancer cells modulates
CITED4 Gene
CITED4 Gene
cited4 gene
163732
The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1, Mutations in this gene are a cause of cardiac septal defects, Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene,
· CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 [ human] Gene ID: 163732 , updated on 8-Jul-2021 Summary
PURPOSE: CITED4 is one member of a family of transcriptional cofactors several of which are deregulated in a variety of tumors including colorectal cancer CRC We modulated CITED4 expression in vitro and analyzed the associated phenotypic and gene expression changes METHODS: CITED4-overexpressing and shRNA-mediated knockdown cell lines and control cell lines were established in the CRC cell line SW480, The cells …
Cited4 is related to cardiogenic induction and maintenance
Functional Associations, CITED4 has 3,028 functional associations with biological entities spanning 8 categories molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA extracted from 61 datasets,
CITED2 Gene – GeneCards
· CITED4 is one member of a family of transcriptional cofactors several of which are deregulated in a variety of tumors including colorectal cancer CRC We modulated CITED4 expression in vitro and analyzed the associated phenotypic and gene expression changes
Hypermethylation and transcriptional downregulation of the
Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 4 CITED4 Gene ID: 163732 Human, CITED4 Synonyms: CITED4, cited4, cited4,L, Cited4 Vector type: Lentiviral Vector Vector backbone: pCLIP-dual-SFFV-ZsGreen Resistance Gene: Ampicillin, Zeocin Selection Marker: Puromycin Promoter: SFFV Promoter, U6 Promoter Fusion Tag: ZsGreen