empagliflozin chemical structure
Empagliflozin BI-10773 is a potent and selective SGLT-2 inhibitor with IC50 of 3,1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6,;IC50 value: 3,1 nM [1];Target: SGLT-2Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 SGLT-2, which is found almost exclusively in the proximal tubules of nephronic components in the kidneys, SGLT-2 accounts for about 90 percent of glucose reabsorption into …
Boiling Point : 664,5±55,0 °C at 760 mmHg
Empagliflozin Chemical Structure CAS NO, 864070-44-0 Empagliflozin is a potent, selective sodium glucose co-transporter-2 inhibitor that is in development for the treatment of type 2 diabetes,
Empagliflozin
Empagliflozin-d4
Substance Name: Empagliflozin [USAN:INN]
Empagliflozin
Empagliflozin R-Isomer, PubChem CID, 73151030, Structure, Find Similar Structures, Molecular Formula, C23H27ClO7, Synonyms, Empagliflozin R-Isomer,
Molecular Formula : C23H27ClO7
7 lignes · Empagliflozin is a C-glycosyl compound consisting of a beta-glucosyl residue having a 4-chloro-3-
Molecular Formula : C23H27ClO7
864070-44-0 – OBWASQILIWPZMG-QZMOQZSNSA-N – Empagliflozin [USAN:INN] – Similar structures search, synonyms, formulas, resource links, and other chemical information,
We compared canagliflozin empagliflozin and dapagliflozin with respect to chemical structure and pharmacological properties to explain the observed differences in preventing acute kidney injury and put forward the hypotheses of the potential mechanisms of different effects of SGLT2 inhibitors on acute kidney injury Given the raising clinical use of SGLT2 inhibitors our review should stimulate further basic science …
Empagliflozin
empagliflozin chemical structure
· Empagliflozin is a potent and competitive SGLT-2 inhibitor with an excellent selectivity profile and the highest selectivity window of the tested SGLT-2 inhibitors over hSGLT-1, Empagliflozin inhibits the uptake of [14C]-alpha-methyl glucopyranoside AMG via hSGLT-2 in a dose-dependent manner with an IC50 of 3,1 nM, but is less potent for other SGLTs IC50 range: 1100-11000 nM, [3H]-Empagliflozin displays a high affinity for …
Empagliflozin Synonyms: BI 10773 Cat, No,: HY-15409 Purity: 99,93%, Data Sheet SDS Handling Instructions, Empagliflozin BI 107730 is a selective sodium glucose cotransporter-2 SGLT-2 inhibitor with an IC50 of 3,1 nM for human SGLT-2, For research use only, We do not sell to patients,
Structure, properties, spectra, suppliers and links for: Empagliflozin-d4, Jump to main content Jump to site nav, Home; About us; Membership & professional community; Campaigning & outreach; Journals, books & databases ; Teaching & learning; News & events; Locations & contacts; Home; About us; Web APIs; Help; Sign in; ChemSpider Search and share chemistry, For medical information relating to
Empagliflozin, sold under the brand name Jardiance among others, is a medication used together with diet and exercise to treat type 2 diabetes, It can be prescribed instead of metformin and has benefits over sulfonylureas, It may be used together with other medications such as metformin or insulin, It is not recommended for type 1 diabetes, It is taken by mouth, In view of recent trial evidence, it is expected to soon receive licence to be …
Manquant :
chemical structure
Name: Empagliflozin CAS#: 864070-44-0 Chemical Formula: C23H27ClO7 Exact Mass: 450,14453 Molecular Weight: 450,91 Elemental Analysis: C, 61,26; H, 6,04; Cl, 7,86; O, 24,84
Chemical Structure Description, A chemical structure of a molecule includes the arrangement of atoms and the chemical bonds that hold the atoms together, The Empagliflozin BI 10773 molecule contains a total of 61 bonds There are 34 non-H bonds, 12 multiple bonds, 6 rotatable bonds, 12 aromatic bonds, 1 five-membered rings, 3 six
Empagliflozin R-Isomer
Empagliflozin
Empagliflozin BI 10773
Empagliflozin BI 10773
Empagliflozin
· Empagliflozin BI-10773 is a potent and selective SGLT-2 inhibitor with IC50 of 3,1 nM, exhibits >300-fold selectivity over SGLT-1, 4, 5 and 6, Phase 3, Phase 3, Size
The SGLT2 Inhibitor Empagliflozin Might Be a New Approach
Empagliflozin BI 10773 Structure
Empagliflozin